Reaper can be used as a video editor.  I have no idea as to how accessible that particular functionality is. Most who use Reaper with a screen reader also use the Open Source Accessibility for the Reaper Application (OSARA) with it.

If you want details on using Reaper and any of its functions with a screen reader, you would be well advised to join the RWP - Reapers Without Peepers Group and ask away.
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Brian - Windows 10, 64-Bit, Version 21H1, Build 19043

The stoical scheme of supplying our wants by lopping off our desires is like cutting off our feet when we want shoes.

         ~ Jonathan Swift (1667-1745)