Yes there is
http://batsupport.com/unsupported/dosbox/
there is a list at
talking-dosbox+subscribe@...
the author is at
guilevi2000@...
There are versions for nvda, and others, using com0com, you are able to make a vertual serial port with the vertual braille n speak emulator there is one for mbrola and a standard one and the right configs you can go and do things.
there is also a way to upload to the thing to
in fact here is my extra notes
dosbox stuff
Site: batsupport.com [176.9.155.71]
User: josh
Password: draktyid3
http://batsupport.com/unsupported/dosbox/



note you may have to ask the list or email the writer of this thing to see what all the info is now.
it uses a branch of dosbox called dosbox daum which from my understanding uses directx as its code base and has a few other features.