You can launch narrator, but you might need a USB audio device. It goes
to mine, though I have multiple audio devices, so maybe if I pulled it,
the internal sound card would work instead. Use Narrator to set up, then
when you're booted, launch your portable copy of NVDA and then tell it
to install and check the box about using portable settings on your
installed copy. Be sure to tell it to keep all the addons and such when
you generate your portable copy. I had to reset twice within a week
because of a dumb Windows update thing, and that's what I did. Hope that
helps.