What update are you trying to apply?
I'd also suggest you do a web search on the specific KB number of the update and the error code you've given. Sometimes with cumulative updates it's easiest to ignore the issue until the next one comes out, as they will frequently work (and no one really knows why).
Brian - Windows 10 Home, 64-Bit, Version 1803, Build 17134
A little kindness from person to person is better than a vast love for all humankind.
~ Richard Dehmel