This evening when I launched NVDA 2018.2.1 and Add-On Updater popped up, indicating that it had an update for itself, it was impossible to interact with the checkbox, even using a mouse, and thus the update could not be completed.  I had to cancel out of the Add-On Updater dialog.

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Brian - Windows 10 Home, 64-Bit, Version 1803, Build 17134  

    The psychology of adultery has been falsified by conventional morals, which assume, in monogamous countries, that attraction to one person cannot co-exist with a serious affection for another.  Everybody knows that this is untrue. . .

           ~ Bertrand Russell