I am not quite sure what you're asking, as creating the material that will be burned to optical media is completely separate from the burning.
I would suggest you take a look at Audacity, which is immensely popular, powerful, open-source and there are lots of tutorials out there for using it with a screen reader.
Brian - Windows 10 Home, 64-Bit, Version 1809, Build 17763
A great deal of intelligence can be invested in ignorance when the need for illusion is deep.
~ Saul Bellow, To Jerusalem and Back