The simple answer is, "Yes."
Either command set should work regardless of the mode set as the default. People have discussed "mix and match" here on many occasions when they find the shortcut sequence from "the other layout" easier for a few things they do frequently.
Brian - Windows 10 Home, 64-Bit, Version 1809, Build 17763
A great deal of intelligence can be invested in ignorance when the need for illusion is deep.
~ Saul Bellow, To Jerusalem and Back