Do one, the other, or both of these programs have installable versions in addition to portable versions?
If they do, the first thing to try is to install the installable version and see if it interacts (or doesn't interact) with NVDA in the same way.
Brian - Windows 10 Pro, 64-Bit, Version 1809, Build 17763
Puritanism: The haunting fear that someone, somewhere, may be happy.
~ H.L. Mencken