What web browser is set as your default? It would be worth testing to see if this might somehow be linked to the browser being used, as odd as that might seem.
The more you can narrow this down to a specific set of circumstances the better.
I can imagine NVDA shutting down if the only thing being seen in the run dialog were to be NVDA. Are you absolutely, positively certain that the entire URL was there?
Brian - Windows 10 Pro, 64-Bit, Version 1909, Build 18363
Power is being told you're not loved and not being destroyed by it.