Windows 10 1903
According to the document:
Most settings can be changed in configuration profiles except for those in the General category of the NVDA Settings dialog, which apply to the entirety of NVDA.
However I found that some settings are not set based on specific profile.
voices of Windows onecore
1. I have a female American English voice set on main configuration.
2. I activate second profile
And I have a male British voice set
3. If I switch off second profile and go back to default profile, it kept the male voice, and I have to manually switch back to the female voice.
I would like to know if this is an issue.
If not, I would like to file a feature request on issue page.