What e-mail client are you using. Generally, when one has focus on click-through text links the status bar at the bottom of the window frame will show the actual naked URL text. The problem being that it will likely be impossible to maintain focus on both things at once, which is one of the conundrums associated with using a screen reader.
Brian - Windows 10 Pro, 64-Bit, Version 2004, Build 19041
A gentleman is one who never hurts anyone's feelings unintentionally.
~ Oscar Wilde