As a general statement, you want your function keys to act as function keys if you are a screen reader user, so if they have any sort of "media keys" feature enabled by default it should be disabled via whatever method your particular machine requires. --
Brian -Windows 10 Pro, 64-Bit, Version 20H2, Build 19042
The depths of denial one can be pushed to by outside forces of disapproval can make you not even recognize yourself to yourself.