Then, my next suggestion, since it's reasonably easy, is doing an uninstall and reinstall of NVDA 2020.4.

If that doesn't fix things (and definitely try the steps noted before for the new install, just for good measure), then I start looking at the Windows and/or Chrome side of the equation.

Heaven knows that NVDA and Chrome can and do play very well together when everything is "as it should be."
--

Brian - Windows 10, 64-Bit, Version 21H1, Build 19043  

I do not understand why some seek to separate a person from their actions.  The self is composed of an individual’s thoughts, actions, and expression, which are contained in and actuated by the body.  What you do and say is the clearest indicator of who you are.

      ~ Brian Vogel