Another thought, and that's all it is, is looking into whether the program you intend to use allows it's own shortcuts to be tweaked.
Since you use NVDA everywhere it makes little sense to redefine what you're already familiar with. But if you're not yet familiar with the specific command structure of the program you're going to use, and it's possible to remap, you might want to consider it.
Brian - Windows 10, 64-Bit, Version 21H1, Build 19043
I do not understand why some seek to separate a person from their actions. The self is composed of an individual’s thoughts, actions, and expression, which are contained in and actuated by the body. What you do and say is the clearest indicator of who you are.
~ Brian Vogel