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Remove McAfee, for starters.  It would not shock me, one bit, if that fixes the problem right there.

You have never mentioned what comes back if you hit the Windows Key, type winver, and hit enter.  Knowing the Windows Version and build is a basic piece of information.  Also the make and model of the PC is a bit help.  Essentially, when seeking help on technical issues one really needs to offer the information about the ecosystem in use:
1. Make & Model of PC 

*Dell Inspiron 3505

Device name DESKTOP-9ECR6D3 Pen and touch Touch support with 256 touch points

2. Windows version and build

*Edition Windows 10 Home Experience Windows Feature Experience Pack 120.2212.3530.0

3. Version for each piece of software believed to be involved (NVDA, Word (or Office as a whole), and Windows)

It affects Microsoft Word and Outlook -- which is what I use...

I presume your Office is an installed version, as that's what most universities offer.  If it's not, then you would not be working with Word as a program, but in a web browser as a web app.

*Microsoft is download -- installed on the computer. 
--

Brian - Windows 10, 64-Bit, Version 21H1, Build 19043  

Nothing in all the world is more dangerous than sincere ignorance and conscientious stupidity.

         ~Martin Luther King, Jr.