On Fri, Dec 10, 2021 at 12:09 AM, Mary Otten wrote:

The fn key, NO!

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OK.  I am not going to argue with anyone's personal experience that differs from mine.  I am not all seeing, but I have touched a lot of computers (and their keyboards) since 1981.

There are multiple close window shortcuts, including, but not limited to ALT + F4 (but which also closes the running program in some cases), ALT + FN + F4, ALT + Spacebar followed by C.  There are probably others, too.  And all of these are Windows-level keyboard shortcuts, not program level, so they should be able to be used regardless of the window that has focus.
 
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Brian - Windows 10, 64-Bit, Version 21H1, Build 19043  

Science has become just another voice in the room; it has lost its platform.  Now, you simply declare your own truth.

       ~ Dr. Paul A. Offit, in New York Times article, How Anti-Vaccine Sentiment Took Hold in the United States, September 23, 2019