It's probably report mouse shape changes setting.

Open mouse settings, control NVDA m, Then read the current line.  I think you are on the setting to turn this on and off.  if it is checked, uncheck it with the space bar.

Tab to and activate the o.k. button.

Gene

This is a long explanation, but, as you will see, knowing what I am going to say will help you work in certain kinds of dialogs more efficiently.  And if you don't know how to move through these dialogs, knowing what I will describe will help you look around unfamiliar programs, which is a valuable skill.

You hear over and over that you should press apply, then ok. in dialogs where both are present for any time you change something.  That is a minor misconception, but it is perhaps the most widespread one I've seen regarding Windows use.  This widespread belief also shows how people don't use logic in figuring out computer operations.  Why are both available if the first is simply redundant?  This question arises, or it should,  when you hear this constant misconception stated. 

It does no harm to do this when there is no need, but apply usually doesn't have to be pressed if you make a change and then you want to leave the dialog and save the change.

In a multipage dialog, where one of the items is a sort of bar you move through with the arrow keys, where you might hear things like general, options, advanced and where every item you move to changes what you see in the dialog to let you work with those settings, you can make changes in one part of the dialog, general, for example, then press apply to save them, stay in the dialog, move to advanced, for example, make changes, and if you are finished, press ok to save and leave the dialog in one step.

Control tab and control shift tab may also move you from one part of such a dialog to another and at times, using both control tab will move you and using the right and left arrow keys will move you, at times you can only move using control tab and shift control tab, in other dialogs, only the left and right arrow will move you.  it depends on how the dialog is constructed.

The NVDA settings dialog is that kind of dialog.  But instead of the left and right arrow, you use the up and down arrows to move through categories. 

Open the NVDA menu, control n, then open preferences.  In preferences, open settings.

You are now in a dialog where you can move to categories and then tab through the dialog and make changes in that category.  if you use the apply button, you are taken to the categories list again and the settings have been saved while you remain in the dialog, ready to make other changes in other categories.  Wen you make the last change you want to make anywhere in the dialog, if you use ok, your last settings or setting whatever you did in the category you just worked in, will be saved and the dialog will close.  All your previous settings were already saved.  It’s a convenience feature to allow you to make as many changes as you like in a category, apply them, make changes in a new category, apply them, etc. without having to use ok, leave the dialog every time you want to save changes and work in a new category.

Also, if you use apply, cancel won't revert what you changed.  Apply is just that, apply, it does what ok does but it doesn't close the dialogue.  So when you make changes, don't use apply unless you are sure, just as you wouldn't use ok unless you are sure.

Gene

It's probably report mouse shape changes setting.

Open mouse settings, control NVDA m, Then read the current line.  I think you are on the setting to turn this on and off.  if it is checked, uncheck it with the space bar.

Tab to and activate the o.k. button.

Gene